I had an engine years back with a milled head and o-rings, and because everything was cut down the head was thinner, so the studs extended too far to use acorn nuts, so I had to use regular nuts. Coolant wasn't leaking around the copper washers, it was coming up through threads and out the top.
I could have cut down the studs and used acorn nuts, but I decided to try an anaerobic sealant. It was a Loctite thread sealant, but I can't remember the exact name. It's basically like teflon tape in liquid form. It worked great.